Before drying-swelling tests, the sample (WBC-g-PNIPAM or native WBC sheet) was immersed in deionized water and shaken at room temperature. After 12 h the sample was taken out, gently removing the excess of water on the sample, and placed in an open beaker at room temperature, and its mass was followed to measure the water loss. PNIPAM hydrogels are widely used in research on tissue engineering. Cells harvested from patients can be grown on PNIPAM or PNIPAM-coated substrates to form viable cell sheets, which can then be layered to form a tissue (Cooperstein and Canavan, 2010; Cooperstein et al., 2017).
ties of PNIPAm have been widely researched with typical thermal transitions occurring around 32 8C,13,17 above which there is a dramatic reduction in volume. Hydrogels contain-ing PNIPAm have been used to create bending actuators which exhibit up to 1408 bending angle,13 drug-release microvalves with 38% material shrinkage,18 photo-
Compared to the chemically crosslinked PNIPAM-based hydrogel, the PNIPAM-clay-PDAEA hydrogel exhibited excellent stretchability and elasticity due to the physically crosslinked network. The incorporation of polypetide endowed the material with excellent controllable adhesiveness and good biocompatibility.
and a fragrance. The Phytacare® Alginate Hydrogel is packaged in 30 or 50 ml polypropylene airless pump containers. Intended Use of the Device: Phytacare® Alginate Hydrogel Wound Dressing is an Alginate Hydrogel that is indicated for the management of diabetic ulcers, foot ulcers, Ist PNIPAM-based Smart Surfaces for Cell Sheet Tissue Engineering Thermosensitive polymer, can be used to form a hydrogel. Aqueous polymer solution undergoes a phase transition from a soluble to an insoluble state when the temperature is raised to ca. 32 °C.
Poly(N-isopropylacrylamide) (variously abbreviated PNIPA, PNIPAAm, NIPA, PNIPAA or PNIPAm) is a temperature-responsive polymer that was first synthesized in the 1950s.It can be synthesized from N-isopropylacrylamide which is commercially available.
the LCST, PNIPAm hydrogel exhibits a hydrophobic surface and cells can attach and proliferate on it. With decreasing temperature below the LCST, the hydrogel surface becomes hydrophilic and the cell sheet detaches spontaneously from the surface without enzyme digestion, which may damage the cell membrane . The harvested cell sheet maintains the
Dec 01, 2016 · Read "A Multiresponsive Anisotropic Hydrogel with Macroscopic 3D Complex Deformations, Advanced Functional Materials" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. UV/VIS Spectrometer, PerkinElmer, USA). Briefly, swollen hybrid hydrogel sheet and macroporous PNIPAM hydrogel sheet of the same size were put onto a glass slide respectively. The excess water on the glass slide was removed by using Kim wipes to make sure the hydrogel sheet attached to the glass slide.
Thermoresponsive hydrogels were successfully prepared from poly(N-isopropylacrylamide)-based polymers with different architectures (linear, branched, or hyperbranched). The macromolecular architectures strongly influence the internal structure of the hydrogels, therefore modulating their thermoresponsive and rheological properties.
Dec 01, 2016 · Read "A Multiresponsive Anisotropic Hydrogel with Macroscopic 3D Complex Deformations, Advanced Functional Materials" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Here, we report a simple and novel method to prepare graphene oxide/reduced graphene oxide (GO/RGO) nanocomposite hydrogel-based deformable actuators by local electrochemical reduction of homogeneous poly(N-isopropylacrylamide)/GO (PNIPAM/GO) hydrogels. GO nanosheets in PNIPAM/GO hydrogels can be reduced in an electrolytic cell made of two ...
self-folding using the hybrid hydrogel sheet with a - temper ature-responsive hydrogel. The hybrid hydrogel sheet was composed of pNIPAM-AAc (dot patterned and blue region in figure 2) and SU-8 (white region in figure 2). pNIPAM-AAc is known as a stimuli-responsive hydrogel with responsive-ness to temperature and/or pH. Supplementary Figure S1. Preparation of composite gel sheets and their transformation in helical structures. a, Schematic of the photolithographic patterning of the hydrogel sheet. A sheet of PNIPAm gel (a primary gel or PG) is swollen with a monomer mixture, sandwiched between the two glass slides, and exposed through a
Dec 29, 2017 · By proper ion-transfer-printing on 1D hydrogel strips, 2D hydrogel sheets, and 3D hydrogel blocks, the hydrogel samples can undergo interesting shape deformations from 1D to 2D, 2D to 3D and simple 3D to complex 3D shapes (Figure 2c) (Adv. Funct. Mater. 2016, 26, 4491-4500). ﬁgure 1. Speciﬁcally, we utilized co-polymerized pNIPAM-AAc hydrogels which reduces the response time as compared to single component pNIPAM hydrogels due to increased hydrophilicity [43, 44] and the AAc component also makes the hydrogel pH responsive . Our approach utilizes the fact that bending of hydrogel thin ﬁlms depend on three The swelling properties and thermal transition of hydrogels can be tailored by changing the hydrophilic-hydrophobic balance of polymer networks. Especially, poly(N-isopropylacrylamide) (PNIPAm) has received attention as thermo-responsive hydrogels for tissue engineering because its hydrophobicity and swelling property are transited around body temperature (32 °C).